WebFeb 16, 2024 · 1 Introduction. Single-cell RNA sequencing allows researchers to measure transcriptome-wide gene expression at single-cell resolution and has gradually transformed our understanding of cell biology and human diseases [].Despite the unprecedented power of scRNA-seq, processing single-cell data are inherently difficult, especially considering … WebJan 15, 2024 · Researchers from the University of Milano present ASGAL (Alternative Splicing Graph ALigner): a tool for mapping RNA-Seq data to the splicing graph, with the specific goal of detecting novel splicing events, involving either …
A Bayesian approach for accurate de novo transcriptome assembly …
WebDec 1, 2024 · Graph representation learning means to find a meaningful, potentially low-dimensional, representation of nodes from the complex relations present in a graph. This requires a map from each node in the graph to a vector space, which … WebOct 31, 2024 · Normalization of RNA-Seq data has proven essential to ensure accurate inferences and replication of findings. Hence, various normalization methods have been proposed for various technical artifacts that can be present in high-throughput sequencing transcriptomic studies. In this study, we set out to compare the widely used library size … is there still native american tribes today
Visualization and analysis of RNA-Seq assembly graphs
WebHere, we propose a single-cell model-based deep graph embedding clustering (scTAG) method, which simultaneously learns cell–cell topology representations and identifies cell … WebApr 1, 2024 · This work aims to initiate this trend by highlighting the potential benefits of using these computational techniques in the recovery of GRNs from single cell RNA sequencing or bulk sequencing based gene expression data. GRNs are directed graphs that capture the direct dependence between transcription factors (TFs) and their target … WebThe protocol of RNA-seq starts with the conversion of RNA, either total, enriched for mRNA, or depleted of rRNA, into cDNA. After fragmentation, adapter ligation, and index ligation, … ikea thermos jugs