Tanshinone iia溶解度

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August undefined, 2024

WebJan 2, 2024 · Tanshinone IIA, one of the most abundant constituents of the root of Salvia miltiorrhiza, protects rat myocardium-derived H9C2 cells against apoptosis. Treatment of … Web腔隙性脑梗死属于特殊性缺血性脑卒中，早期无典型症状，且病情进展相对缓慢，但若未得到及时有效治疗，则极易导致病情持续进展，可能引发严重不良结局 [] 。目前，临床针对腔隙性脑梗死患者尚无特效疗法，多于降压、降脂、抗血小板聚集等基础治疗前提下给予药物干预，其中，西洛他唑 ...

Tanshinone IIA - an overview ScienceDirect Topics

WebDoxorubicin, one of the original anthracyclines, remains among the most effective anticancer drugs ever developed.Clinical use of doxorubicin is, however, greatly limited by … WebApr 28, 2024 · Tanshinone IIA (TIIA), derived from Salvia miltiorrhiza Bunge, has been shown to have antitumor effects on various tumors by inducing apoptosis, triggering autophagy, and inhibiting angiogenesis. 12–15 In the present study, we found that TIIA was a potential candidate for enhancing NK cell-mediated killing of NSCLC cells by a luminescent ... prince george\\u0027s county census

The application of omics techniques to evaluate the effects of ...

WebNov 8, 2024 · Tanshinone IIA (Tan IIA) is an important characteristic component and active ingredient in Salvia miltiorrhiza, and its various aspects of research are constantly being updated to explore its potential application. In this paper, we review the recent progress on pharmacological activities and the therapeutic mechanisms of Tan IIA according to … WebSep 4, 2024 · Liver diseases, such as liver fibrosis, have become a threat to human life worldwide. Acute or chronic liver injury can induce liver fibrosis, which exhibits an increased expression of type I collagen and smooth muscle alpha-actin (α-SMA). 1 Salvia miltiorrhiza, which is an herb used in traditional Chinese medicine, can play a regulatory role in liver … prince george\\u0027s county careers

Tanshinone IIA SpringerLink

WebJun 23, 2024 · Tanshinone IIA (Tan IIA), an active ingredient of Danshen, is a well-used drug to treat cardiovascular diseases. Currently, the mechanisms involved remain poorly understood. Given that many actions of Tan IIA could be similarly achieved by hydrogen sulfide (H 2 S), we speculated that Tan IIA might work through the induction of … WebTanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF / VEGFR2 . IC 50 & Target. VEGF/VEGFR2 [1] In Vitro. The anti-tumor effect of Tanshinone … prince george\u0027s county cdbgWebTanshinone IIA is a major tanshinone isolated from Salvia miltiorrhiza. Inhibits NF- κ B and AP-1 DNA binding. Exhibits cytotoxic activity in a number of different cancer cells. Inhibits β -amyloid aggregation and protects PC12 cells from β -amyloid-induced apoptosis. Displays antioxidant and anti-inflammatory properties. pleasant view dairy highland

"WebNov 5, 2024 · Tanshinone IIA (tan-IIA) is the main fat-soluble component of Salvia miltiorrhiza. Modern pharmacological study shows that tan-IIA has anti-inflammatory and anti-oxidant activities. Tan-IIA induces remarkable cardioprotective effects via enhancing angiogenesis which may serve as an effective treatment against cardiovascular diseases … " - Tanshinone iia溶解度

Tanshinone iia溶解度

Unveiling the Mode of Action of Two Antibacterial Tanshinone …

WebTanshinone IIA ≥97% (HPLC); CAS Number: 568-72-9; Synonyms: 1,6,6-Trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione,Dan Shen ketone; find Sigma-Aldrich-T4952 MSDS, related peer-reviewed papers, technical documents, similar products & more at … WebMar 14, 2024 · Tanshinone IIA is a representative monomeric compound in S. miltiorrhiza. However, due to the poor water solubility, its water-soluble derivative, sodium tanshinone …

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Tanshinones are a class of chemical compounds. Examples include dihydrotanshinone, tanshinone I, or tanshinone IIA. These compounds are all naturally occurring and can all be isolated from Salvia miltiorrhiza. Dihydrotanshinone I has been reported to have cytotoxicity to a variety of tumor cells. Web1. Previous reports implied that tanshinone IIA (TSA) may offer potential benefits for Crohn's disease (CD). However, the detailed pharmacokinetic behavior of

WebMar 6, 2013 · Solid dispersions of tanshinone IIA (TanIIA) using hydroxyapatite (HAp) as the dispersing carrier (TanIIA-HAp SDs) were prepared by the solvent evaporation method. The formed solid dispersions were characterized by scanning electron microscopy (SEM), differential scanning calorimetry analysis (DSC), X-ray powder diffraction (XRPD) and … WebOct 3, 2013 · The optimum extraction process of tanshinone IIA was as follows: addition of a 10-fold amount of 80% ethanol, one-time extraction, and extraction time of 45 minutes. …

WebAccording to the system network analysis of the corresponding ways, the effect of Tan IIA on UC in mice is mainly through the regulation of taurine and hypotaurine metabolism. … WebJan 14, 2024 · Recently, it was reported that tan IIA could have a wide range of antitumor effects on several human tumor cell lines, but the research of the mechanism of tan IIA is …

WebJul 31, 2015 · A mixture of tanshinone IIA (29.4 mg, 0.1 mmol), pyrrolidine (15.6 mg, 0.2 mmol), 36% formaldehyde solution (18 mg) in acetic acid (20 mL) was stirred at 20 °C for 1 h, then stirred under reflux at 90 °C for 9 h. Next, the solution was cooled and washed three times with sodium carbonate solution, and extracted with dichloromethane. ...

Web案例分析：. 1. 问：从哪里可以查到标准物质的结构、物理化学特性？答：标准品的说明书大多附有结构，化学药品的可以通过欧洲药典二部查阅。 pleasant view dairy ukiah caWebAug 22, 2024 · 3.2. Tanshinone IIA Can Reduce Radiation-Induced Oxidative Stress in Cardiomyocytes. To explore whether tanshinone IIA has the ability to exert antioxidant activity, we performed ROS and SOD activity measurements, as shown in Figures 2(b) and 3.The experimental results showed that ROS increased in the H9c2 cells (), while SOD … pleasant view dairy highland indianaWebApr 14, 2024 · CNN —. The National Weather Service confirmed Wednesday the tornado that injured 23 in Bell County, Texas, was an EF-3 with 165 mph winds. The EF-3 was one of … prince george\u0027s county central committeeWebSix compounds namely, tanshinone IIA (1), carnosic acid (2), rosmarinic acid (3), salvianolic acid B (4), baicalein (5), and glycyrrhetinic acid (6) were screened for their anti-SARS-CoV-2 activities against both the spike (S) and main protease (Mpro) receptors using molecular docking studies.Molecular docking recommended the superior affinities of both … pleasant view developersWebHerein, tanshinone IIA (TAN) delivery silk fibroin scaffolds were prepared for efficient cartilage defect repair by bioactivities of TAN. By incubating with the TAN delivery silk fibroin scaffold, the transcription of the chondrocytic activity-related genes was enhanced in chondrocytes, and it also can inhibit cell apoptosis and reduce the ... pleasant view daycareWebMar 2, 2024 · Explore historical sites, make your own art and discover a few of the unique things that make our Village special and plan your getaway now! prince george\\u0027s county central servicesWebTanshinone IIA (Tan IIA) has a previously confirmed antitumor activity against breast cancer in addition to its well-known cardioprotective effect. In our study, molecular docking reveals the potential activity of Tan IIA as a DNA intercalator and Topo II inhibitor as a recommended possible mechanism of action compared to Dox as a reference drug. prince george\u0027s county central services