Tfeb s211

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August undefined, 2024

Web4 Mar 2024 · The master regulator of lysosome biogenesis, TFEB, is regulated by MTORC1 through phosphorylation at S211, and a S211A mutation increases nuclear localization. … Web1 Aug 2024 · This allows mTORC1-dependent phosphorylation of TFEB including phosphorylation of TFEB at serine 211 (S211). Phosphorylation in S211 promotes …

The transcription factors TFE3 and TFEB amplify p53 dependent ...

Web24 Jan 2024 · Recently, a new Ca 2+ signaling mechanism originating from the lysosome has been involved in the modulation of the transcription factor EB (TFEB) , a master gene … WebAs the nuclear localization of TFEB is tightly controlled by mTORC1-dependent phosphorylation of TFEB on serine 211, which results in its interaction with 14-3-3 … memories dragonflight

Cells Free Full-Text TFEB Biology and Agonists at a Glance - MDPI

Web本发明涉及生物医学领域，具体是一种与tfeb结合并调节tfeb磷酸化和核转位的蛋白多肽。tfeb是一种转录因子，在调控细胞溶酶体生物发生、酸化和功能中具有重要作用。其 … Web3 Aug 2024 · The host cell utilizes nucleocytoplasmic shuttling of TFEB to control the expression of its target genes. The mammalian target of rapamycin 1 (mTORC1) complex … Web5 Jan 2024 · TFEB regulation by Torin1 has been attributed to changes in S211 phosphorylation, and mutations of serine 211 to alanine increase TFEB nuclear … memories dragonflight wow

Phospho-TFEB (Ser211) (E9S8N) Rabbit mAb - Cell …

National Center for Biotechnology Information

WebTFEB at S142 (Settembre et al., 2012) and S211 (Martina et al., 2012; Roczniak-Ferguson et al., 2012), which promote cytosolic retention of TFEB; S211 phosphorylation promotes … Web5 Feb 2024 · cytoplasmic retention of TFEB. When mTORC1 was inhibited, S211 is dephosphorylated. and TFEB enters the nucleus. T orin1 is an mTOR inhibitor [84]. When … memories dreamsWebThe activity of TFEB is tightly linked to nutrient availability via protein phosphorylation. In the presence of nutrients TFEB is phosphorylated by mTOR on S142 and S211 serine … memories do not open tour

"Webregulates TFEB by promoting its phosphorylation on serine 211 (S211), a phosphorylation site we previously identified as a down-stream target of mTORC1 that controls nuclear … " - Tfeb s211

Tfeb s211

The IRG1/itaconate/TFEB axis: A new weapon in …

Web30 Mar 2024 · Among factors that could possibly activate TFEB/TFE3 signaling upon ESCRT-I deficiency, we excluded lysosomal cholesterol accumulation and Ca2+-mediated … Web一种与tfeb结合并调节tfeb磷酸化的蛋白多肽及其应用专利检索，一种与tfeb结合并调节tfeb磷酸化的蛋白多肽及其应用属于抗肿瘤药专利检索，找专利汇即可免费查询专利，抗肿瘤药专利汇是一家知识产权数据服务商，提供专利分析，专利查询，专利检索等数据服务功能。

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WebAnti-phospho TFEB (Ser142), Cat. No. ABE1971-I, is a highly specific rabbit polyclonal antibody that targets Transcription factor EB phosphorylated on Serine 142 and has been … WebThe Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors. …

Web27 Aug 2024 · Furthermore, expression of TFEB-GFP in HEK293 cells was followed by autophinib sensitive expression of P-Ser211 TFEB-GFP. These results showed that … Web11 Jul 2024 · These observations were confirmed using stable cell lines expressing similar levels of full length WT and mutant TFEB-GFP (Fig. 3b) which, in contrast to the cargo …

WebLysosomal biogenesis is coordinated by a key transcription factor TFEB ( Napolitano, and Ballabio, 2016 ). Under nutrient-rich conditions, mTOR-mediated TFEB S211 (S211 in … WebS211A Entrez Gene TFEB ( a.k.a. ALPHATFEB, BHLHE35, TCFEB) Tags / Fusion Proteins Myc (C terminal on backbone) 6xHIs (C terminal on backbone) Cloning Information Cloning …

WebPhosphoPlus ® TFEB (Ser211) Antibody Duet #48590 Reviews () Citations (0) Chromatin immunoprecipitations were performed with cross-linked chromatin from Raji cells treated … memories dreams reflections quotesWeb10 Jul 2024 · In this sense, mTOR-dependent phosphorylation of TFEB (S211) is recognized by YWHA/14-3-3 proteins that promote its cytoplasmic retention , but curcumin inhibits … memories flush inWebWe also found that S211 on TFEB was still phosphorylated after TSA treatment, like in DMSO-treated cells, while Torin1 significantly reduced the phosphorylation at S211 (Fig. 5, … memories dreams reflections carl jung pdfWebNational Center for Biotechnology Information memories drift in and out of my mindWeb28 Feb 2024 · TFEB (Transcription Factor EB) is a Protein Coding gene. Diseases associated with TFEB include Renal Cell Carcinoma, Xp11-Associated and Pycnodysostosis.Among … memories fadingWebMTORC1 is thought to phosphorylate TFEB on S21124,25 and also on S142.23 S211 phosphorylation by MTORC1 creates a high afﬁnity binding site for YWHA proteins, … memories filmsWeb10 Jul 2024 · In this sense, mTOR-dependent phosphorylation of TFEB (S211) is recognized by YWHA/14-3-3 proteins that promote its cytoplasmic retention [ 72 ], but curcumin inhibits this phosphorylation, allowing TFEB translocation to the nucleus and enhancing its transcriptional activity [ 71 ]. Notably, curcumin is also effective in chronic kidney disease. memories drive in movie theater